Etoricoxib

Etoricoxib
  • Nomen:Etoricoxib
  • Catalogue No.CPDD2043
  • CAS No.:202409-33-4
  • Pondus hypotheticum:358.8419
  • Formulae chemica:C18H15ClN2O2S
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine.

    SMILES Code:

    O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

    InChi Code:

    InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6- 13)24(2,22)23/h3-11H,1-2H3

    InChi Key:

    MNJVRJDLRVPLFE-UHFFFAOYSA-N

    Keyword:

    Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

    Solubilitas:Solutum in DMSO

    Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)

    Descriptio:

    Etoricoxib est syntheticum, nonsteroidale medicamentum anti-inflammatorium (NSAID) cum antipyreticis, analgesicis et potentialibus proprietatibus antineoplasticis. Etoricoxib specie enzyme cyclooxygenasis-2 (COX-2) obligat et vetat, inde in inhibitione conversionis acidi arachidonici in prostaglandins. Inhibitio COX-2 apoptosin et tumorem cellularum proliferation et angiogenesis inhibere potest.

    Target: COX-2


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