DEL-22379

DEL-22379
  • Nomen:DEL-22379
  • Catalogue No.CPDB3713
  • CAS No.:181223-80-3
  • Pondus hypotheticum:444.55
  • Formulae chemica:C26H28N4O3
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    (Z)-N-(3-((5-methoxy-1H-indol-3-yl) methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl) propanamide

    SMILES Code:

    O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C)C(OC)C=C4)=O)C=C1)CCN5CCCCC5

    InChi Code:

    InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26(22)32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2; 1H3,(H,28,31)(H,29,32)/b22-13+

    InChi Key:

    INQUULPXCZAKMS-LPYMAVHISA-N

    Keyword:

    DEL-22379, DEL22379, DEL 22379, 181223-80-3

    Solubilitas:Solutum in DMSO

    Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)

    Descriptio:

    DEL-22379 potens et selectiva ERK Dimerization inhibitor est. DEL-22379 vetat ERK Dimerizationem sine afficiens ERK phosphorylationem praevenit tumorigenesis ab RAS-ERK iter oncogenis agitatum. Fere 50% hominum malignitates exhibent inordinatas RAS-ERK significantes; inhibere est validum consilium ad interventum antineoplasticum.

    Target: ERK


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