diABZI STING agonist-1 (Tautomerism)

Navê Kîmyayî:

(E)-1-((E)-4-((E)-5-karbamoyl-2-((1-ethyl-3-methyl-1H-pyrazole-5-karbonyl)imino)-7-(3- morfolinopropoksî)-2,3-dîhîdro-1H-benzo[d]imid azol-1-îl)but-2-en-1-îl)-2-((1-etîl-3-methyl-1H-pyrazole-5-karbonîl)imino)-7-metoksi-2,3-dihydro- 1H-benzo[d]imidazole-5-karboksamîd

Koda SMILES:

O=C(N)C1=CC(N/C(N2C/C=C/CN3/C(NC4=C3C(OCCCN5CCOCC5)=CC(C(N)=O)=C4)=N/C(C6= CC(C)=NN6CC)=O)=NC(C7=CC(C)=NN7CC)=O)=C2C(OC)=C1

Koda InChi:

InChI=1S/C42H51N13O7/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43 )56)23-33(60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20-26 (4) 50-55 (32) 7-2) 22-28 (38 (44) 57) 24-34 (36) 62-16-10-11-51-14-17-61-18-15-51/h8- 9, 19-24H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59)/b9 -8+

Bişkojka InChi:

JGLMVXWAHNTPRF-CMDGGOBGSA-N

Keyword:

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Embarkirinî: 

Terîf:

DiABZI STING agonîst-1 Tautomerism (tevlîhev 3) stimulatorek bijartî ya genên înterferonê (STING) agonîstê receptorê ye, bi EC50 130, 186 nM ji bo mirov û mişk, bi rêzê ve.

Armanc: STING