Omarigliptin

Aha kemịkalụ:

(2R, 3S, 5R) -2- (2,5-difluorophenyl) -5- (2- (methylsulfonyl) pyrrolo [3,4-c] pyrazol-5 (2H, 4H, 6H) -yl) tetrahydro-2H -pyran-3-amin

Koodu Ọchịchọ:

N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1

Koodu InChi:

InChi=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11 (18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1

Igodo InChi:

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

Okwu:

Omarigliptin, MK-3102,MK3102,Marizev,1226781-44-7

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)

Nkọwa:

Omarigliptin, nke a makwaara dị ka MK-3102, bụ onye na-egbochi DPP-4 na-eme ogologo oge maka ọgwụgwọ ụdị ọrịa shuga 2 kwa izu. Achọpụtara MK-3102 (omarigliptin) dị ka onye na-egbochi dipeptidyl peptidase 4 (DPP-4) nke nwere ezigbo profaịlụ pharmacokinetic nke nwere ike inye mmadụ otu ugboro kwa izu wee họrọ ya dị ka onye ndoro-ndoro mmepe ụlọ ọgwụ. Omarigliptin nọ ugbu a na mmepe ụlọ ọgwụ nke 3.

Ebumnuche: DPP-4