Ertugliflozin

Aha kemịkalụ:

(1S,2S,3S,4R,5S) -5- (4-chloro-3- (4-ethoxybenzyl) phenyl) -1- (hydroxymethyl) -6,8-dioxabicyclo[3.2.1] octane-2,3 ,4-triol

Koodu Ọchịchọ:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl"

Koodu InChi:

"InChi=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) 18 (25)19 (2 6)21 (11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+ ,21-,22-/m0/s1 "

Igodo InChi:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

Okwu:

Ertugliflozin, PF 04971729, MK-8835,1210344-57-2

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

Ertugliflozin, nke a makwaara dị ka PF-04971729, bụ onye na-egbochi ike na nhọrọ nke onye na-ahụ maka glucose na-adabere na sodium na onye na-akwado ụlọ ọgwụ maka ọgwụgwọ ụdị ọrịa shuga mellitus 2. Nnyocha ụlọ ọgwụ gosipụtara na Ertugliflozin (1-25 mg / ụbọchị) kwalitere njikwa glycemic, ịdị arọ ahụ na ọbara mgbali na ndị ọrịa nwere T2DM na-achịkwa nke ọma na metformin, ma na-anabata ya nke ọma.

Ebumnuche: SGLT-2