Trelagliptin

Aha kemịkalụ:

(R) -2- ((6- (3-aminoperidin-1-yl) -3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1 (2H) -yl) methyl) -4-fluorobenzonitrile succinate.

Koodu Ọchịchọ:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

Koodu InChi:

InChi=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)1 0-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1 /s1

Igodo InChi:

IWYJYHUNXVAVAA-OAHLLOKOSA-N

Okwu:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

Trelagliptin, nke a makwaara dị ka SYR-472, bụ ihe mgbochi dipeptidyl peptidase-4 (DPP-4) na-eme ogologo oge nke Takeda na-emepụta maka ọgwụgwọ ụdị ọrịa shuga 2 (T2D). Otu ugboro kwa izu, ọgwụgwọ SYR-472 na-emepụta mmụba nke ụlọ ọgwụ na ọnụ ọgụgụ dị ukwuu na njikwa glycemic na ndị ọrịa nwere ụdị ọrịa shuga 2. A nabatara ya nke ọma ma nwee ike bụrụ nhọrọ ọgwụgwọ ọhụrụ maka ndị ọrịa nwere ọrịa a. A kwadoro Trelagliptin (Zafatek(®)) na Japan maka ọgwụgwọ ụdị ọrịa shuga mellitus 2 (T2DM).

Ebumnuche: DPP-4