H3B-6527

Aha kemịkalụ:

N- (2-(6- (3- (2,6-dichloro-3,5-dimethoxyphenyl)) -1-methylureido) pyrimidin-4-yl) amino) -5- (4-ethylpiperazin-1-yl) phenyl) acrylamide

Koodu Ọchịchọ:

C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C =C3)=O

Koodu InChi:

InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34- 23-16-24 (33-17-32-23)37(3 )29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2 ,2-5H3, (H,35,40)(H,36,41)(H,32,33,34)

Igodo InChi:

MBWRLLRCTIYXDW-UHFFFAOYSA-N

Okwu:

H3B-6527, H3B 6527, H3B6527, 1702259-66-2

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

H3B-6527 (H3 Biomedicine) bụ onye mmechi FGFR4 ahọpụtara nke ukwuu nwere ọrụ antitumour siri ike na ahịrị cell gbagoro agbagoro na ụmụ oke FGF19.

Ebumnuche: FGFR4