Mirogabalin besylate

Non Chimik:

((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate

Kòd SMILES:

CCC(C1)=C[C@]2([H])[C@@]1([H])C[C@]2(CN)CC(O)=OO=S(C3=CC=CC =C3)(O)=O

Kòd InChi:

InChI=1S/C12H19NO2.C6H6O3S/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8;7-10(8,9) 6-4 -2-1-3-5-6/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15);1-5H,(H,7,8,9) /t9-,10-,12-;/m1./s1

InChi kle:

OKJXJRVWXYRSAN-TXULWXBWSA-N

Mot:

Mirogabalin, Mirogabalin besylate, 1138245-21-2,1138245-13-2, DS-5565, DS5565, DS 5565

Solibilite:DMSO;H2O

Depo: 

Deskripsyon:

Mirogabalin, ke yo rele tou DS-5565, se yon ligand α2δ-1 ke yo te devlope pou doulè ki asosye ak neropati periferik dyabetik, fibromyalji, ak neuralji postherpetic. Li te montre rezilta pwomèt nan Faz II esè klinik pou tretman doulè dyabetik periferik neropatik.

Sib: α2δ-1