DEL-22379
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | Nan Stock | 350 |
| 250 mg | Nan Stock | 600 |
| 1g | Nan Stock | 1200 |
| Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamid
Kòd SMILES:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Kòd InChi:
InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+
InChi kle:
INQUULPXCZAKMS-LPYMAVHISA-N
Mot:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa)
Deskripsyon:
DEL-22379 se yon inibitè ki pisan ak selektif ERK Dimerization. DEL-22379 inibit ERK Dimerization san yo pa afekte fosforilasyon ERK, anpeche tumorigenesis kondwi pa onkogen chemen RAS-ERK. Prèske 50% nan maladi malign imen montre siyal RAS-ERK ki pa reglemante; anpeche li se yon estrateji valab pou entèvansyon antineoplastic.
Sib: ERK
