| CAT br. | Naziv proizvoda | Opis |
| CPD3611 | SB-204990 | SB-204990 je predlijek snažnog inhibitora ATP citrat-liaze SB-201076. SB-204990, kada je štakorima davan oralno, apsorbirao se u sistemsku cirkulaciju, a farmakološki relevantne koncentracije SB-201076 pronađene su u jetri. SB-204990 (25 mg/kg dnevno) također je smanjio razinu kolesterola u plazmi (do 23%) i razinu triglicerida (do 38%) kod pasa, prvenstveno smanjujući lipoprotein niske gustoće u usporedbi s kolesterolom lipoproteina visoke gustoće razine. SB-204990 važan je enzim u kontroli opskrbe supstratom za de novo sintezu lipida i potencijalna meta enzima za hipolipidemijsku intervenciju. |
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