ʻO Omarigliptin

Inoa Kimia:

(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H -pyran-3-amine

SMILES Code:

N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1

Code InChi:

InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1

Ki InChi:

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

huaʻōlelo:

Omarigliptin,MK-3102,MK3102,Marizev,1226781-44-7

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

wehewehe:

ʻO Omarigliptin, ʻike ʻia hoʻi ʻo MK-3102, he mea hoʻopaneʻe DPP-4 ikaika a lōʻihi no ka mālama ʻana i hoʻokahi pule o ka maʻi diabetes type 2. Ua ʻike ʻia ʻo MK-3102 (omarigliptin), he mea ikaika a koho i ka dipeptidyl peptidase 4 (DPP-4) inhibitor me kahi profile pharmacokinetic maikaʻi loa i hiki ke hoʻopaʻa ʻia i hoʻokahi pule i kēlā me kēia pule a koho ʻia ma ke ʻano he moho hoʻomohala lapaʻau. Aia ʻo Omarigliptin i kēia manawa i ka pae 3 o ka hoʻomohala lāʻau lapaʻau.

Pahuhopu: DPP-4