ʻO Ertugliflozin

Inoa Kimia:

(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3 ,4-triol

SMILES Code:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl "

Code InChi:

"InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27 )18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18 -,19-,20+,21-,22-/m0/s1"

Ki InChi:

"MCIACXAZCBVDEE-CUUWFGFTSA-N "

huaʻōlelo:

Ertugliflozin, PF 04971729,MK-8835,1210344-57-2

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

ʻO Ertugliflozin, i ʻike ʻia hoʻi ʻo PF-04971729, he mea hoʻomalu a koho i ka sodium-dependent glucose cotransporter 2 a me ka moho lapaʻau no ka mālama ʻana i ka maʻi diabetes type 2. Ua hōʻike ʻia nā haʻawina hoʻomaʻamaʻa e hoʻomaikaʻi ʻo Ertugliflozin (1-25 mg / lā) i ka mana glycemic, ke kaumaha o ke kino a me ke kahe koko i nā mea maʻi me ka T2DM suboptimally controlled ma ka metformin, a ua ʻae maikaʻi ʻia.

Pahuhopu: SGLT-2