ʻO Trelagliptin

Inoa Kimia:

(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

SMILES Code:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

Code InChi:

InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)1 0-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1 /s1

Ki InChi:

IWYJYHUNXVAVAA-OAHLLOKOSA-N

huaʻōlelo:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

ʻO Trelagliptin, ka mea i kapa ʻia ʻo SYR-472, he mea hoʻopaneʻe dipeptidyl peptidase-4 (DPP-4) hana lōʻihi i kūkulu ʻia e Takeda no ka mālama ʻana i ka maʻi diabetes type 2 (T2D). ʻO ka mālama ʻana iā SYR-472 i hoʻokahi pule i hoʻomaikaʻi nui ʻia i ka hoʻokele glycemic i nā maʻi me ka maʻi diabetes type 2. Ua ʻae maikaʻi ʻia a he koho lapaʻau hou paha ia no nā poʻe maʻi me kēia maʻi. Ua ʻae ʻia ʻo Trelagliptin (Zafatek(®)) ma Iapana no ka mālama ʻana i ka maʻi diabetes type 2 (T2DM).

Pahuhopu: DPP-4