H3B-6527

Inoa Kimia:

N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl))-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl) phenyl)acrylamide

SMILES Code:

C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C) =C3)=O

Code InChi:

InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34- 23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/ h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)

Ki InChi:

MBWRLLRCTIYXDW-UHFFFAOYSA-N

Hua'ōlelo:

H3B-6527, H3B 6527, H3B6527, 1702259-66-2

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

ʻO H3B-6527 (H3 Biomedicine) he mea hoʻopaneʻe FGFR4 i koho nui ʻia me ka hana antitumour ikaika ma FGF19 i hoʻonui ʻia i nā laina kelepona a me nā ʻiole.

Pahuhopu: FGFR4