CB-839

Inoa Kimia:

2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl)acetamide

SMILES Code:

O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4

Code InChi:

InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8- 9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38)

Ki InChi:

PRAAPINBUWJLGA-UHFFFAOYSA-N

huaʻōlelo:

CB-839, CB839, CB 839, 1439399-58-2

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

"ʻO CB-839 an he mea hoʻopaneʻe waha o ka glutaminase, me ka hana antineoplastic hiki. ʻO ka hoʻohana ʻana, ka hoʻonui ʻana i nā cell e ulu wikiwiki nei e hilinaʻi i ka hoʻololi ʻana o ka glutamine exogenous i glutamate a me ka glutamate metabolites e hāʻawi i ka ikehu a hoʻoulu i nā poloka kūkulu no ka hana ʻana i nā macromolecules, pono no ka ulu ʻana a me ke ola.

Kuhikuhi: Glutaminase