Saukewa: GDC-0326
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 1g | A Stock | 1800 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
(S)-2-(2- (1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo [f] imidazo [1,2-d] [1,4] oxazepin-9-yl) oxy) propanamide
Lambar SMILES:
C[C@H](OC1=CC=C2C3=NC(C4=NC=NN4C(C)C)=CN3CCOC2=C1)C(N)=O
Lambar InChi:
InChi=1S/C19H22N6O3/c1-11(2)25-19(21-10-22-25)15-9-24-6-7-27-16-8-13(28-12(3)17(28-12(3)17(2) 20)26)4-5-14(16)18(24)23-15/h4-5,8-12H,6-7H2,1-3H3,(H2,20,26)/t12-/m0/s1
InChi Key:
SIKYDKLGPWRPMZ-LBPRGKRZSA-N
Mabuɗin kalma:
GDC-0326, GDC0326, GDC 0326, 1282514-88-8
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)
Bayani:
GDC-0326 shine mai hanawa mai ƙarfi da zaɓi na α-Isoform na Phosphoinotide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 yana samun babban matakin zaɓi akan sauran kinases. GDC-0326 yana da ƙananan plasma CL a cikin ɗan adam. A cikin dangin PI3 kinase, akwai nau'ikan I PI3K isoforms guda huɗu (α, β, δ, da γ). Daga cikin waɗannan isoforms, PI3KA shine mafi yawan alaƙa da ciwon daji.
Saukewa: PI3K
