IT-901
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 500 |
| 500mg | A Stock | 800 |
| 1g | A Stock | 1200 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H) -pyrimidinedione
Lambar SMILES:
O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S
Lambar InChi:
InChi=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)
InChi Key:
JHOPCCOYRKEHQU-UHFFFAOYSA-N
Mabuɗin kalma:
IT-901, IT901, IT 901, 1584121-99-2
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
"IT-901 shine C-Rel Inhibitor wanda ke Magance Abubuwan Anticancer a cikin Malignancies na Hematologic ta hanyar Kashe NF-κB-Controlled Oxidative Stress Responses. IT-901 yana hana NF-κB subunit c-Rel. IT-901 danne damfara-tare da- Mai watsa shiri yayin da yake kiyaye aikin graft-versus-lymphoma yayin dasawa na allogeneic ƙarin ƙima na IT-901 don kula da ƙwayoyin lymphoma na B-cell ya bayyana kaddarorin antitumor a cikin vitro da in vivo ba tare da iyakancewa ga NF-κB ba. 901 bai haifar da ƙara yawan nau'in oxygen mai aiki a cikin leukocytes na al'ada ba, yana kwatanta kaddarorin masu cutar kansa IT-901 wani sabon magani ne na warkewa don magance ciwace-ciwacen ƙwayoyin cuta na ɗan adam.
Saukewa: NF-kB
