BAY-293
Don binciken kimiyya kawai, ba ga marasa lafiya ba.
Cikakken Bayani
Tags samfurin
Girman Kunshin | samuwa | Farashin (USD) |
Sunan Sinadari:
(R) -6,7-dimethoxy-2-methyl-N- (1- (4- (2- ((methylamino)methyl) phenyl) thiophen-2-yl) ethyl) quinazolin-4-amine
Lambar SMILES:
C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=CC=C4CNC)=CS3
Lambar InChi:
InChi=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4)23 (31-5)12-21 (20)28-16 (2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1
InChi Key:
WEGLOYDTDILXDA-OAHLLOKOSA-N
Mabuɗin kalma:
BAY-293, BAY 293, BAY293
Solubility:
Ajiya:
Bayani:
BAY-293 shine mai hana SOS1 mai ƙarfi wanda ke toshe kunna RAS ta hanyar rushewar hulɗar RAS-SOS1. BAY-293) yana hana hulɗar KRAS-SOS1 tare da IC50 na 21 nM kuma yana da mahimmancin binciken sinadarai don bincike na gaba.
Manufar: SOS1 hanawa