GSK2982772

GSK2982772
  • Suna:GSK2982772
  • Catalog No.:Saukewa: CPDD1123
  • Lambar CAS:1622848-92-3
  • Nauyin Kwayoyin Halitta:377.404
  • Tsarin Sinadarai:Saukewa: C20H19N5O3
  • Don binciken kimiyya kawai, ba ga marasa lafiya ba.

    Cikakken Bayani

    Tags samfurin

    Girman Kunshin samuwa Farashin (USD)
    100mg A Stock 500
    500mg A Stock 800
    1g A Stock 1200
    Ƙarin Girman Girma Samu Magana Samu Magana

    Sunan Sinadari:

    (S) -5-Benzyl-N- (5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo [b]-[1,4] oxazepin-3-yl) -4H-1,2, 4-triazole-3-carboxamide

    Lambar SMILES:

    O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O

    Lambar InChi:

    InChi=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(2) 3-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24) /t14-/m0/s1

    InChi Key:

    LYPAFUINURXJSG-AWEZNQCLSA-N

    Mabuɗin kalma:

    GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3

    Solubility:Mai narkewa a cikin DMSO

    Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).

    Bayani:

    GSK2982772 mai ƙarfi ne kuma zaɓi mai karɓa yana hulɗa da Protein 1 (RIP1) Kinase Specific Clinical Candidate for the Treatment of Inflammatory Diseases. GSK2982772 ne, a halin yanzu a cikin lokaci 2a nazarin asibiti don psoriasis, rheumatoid arthritis, da ulcerative colitis. GSK2982772 yana ɗaure da ƙarfi zuwa RIP1 tare da ƙayyadaddun kinase kuma yana da kyakkyawan aiki don toshe martanin salula masu dogaro da yawa na TNF. RIP1 ya fito ne a matsayin mahimmancin kinase mai mahimmanci wanda aka nuna don tsara ƙumburi ta hanyar kullun da kuma kinase takamaiman ayyuka.

    Saukewa: RIP1


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