Farashin CB-839
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 500 |
| 500mg | A Stock | 800 |
| 1g | A Stock | 1200 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
2- (pyridin-2-yl) -N- (5- (4--6--2- (3- (trifluoromethoxy) phenyl) acetamido) pyridazin-3-yl) butyl) -1,3,4-thiadiazol -2-yl) acetamide
Lambar SMILES:
O=C(NC1=CC=C(CCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4
Lambar InChi:
InChi=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34-) 21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8- 9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38)
InChi Key:
PRAAPINBUWJLGA-UHFFFAOYSA-N
Mabuɗin kalma:
CB-839, CB839, CB 839, 1439399-58-2
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
"CB-839 wani mai hanawa na glutaminase ne na baka, tare da yiwuwar aikin antineoplastic. A kan gudanar da baki, CB-839 zaɓaɓɓe kuma ba tare da canzawa ba yana hana glutaminase, wani enzyme mitochondrial wanda ke da mahimmanci don canza amino acid glutamine zuwa glutamate. Ta hanyar toshe glutamine. Yin amfani da, yaduwa a cikin ƙwayoyin da ke girma cikin sauri yana da lahani ga ciwace-ciwacen da ke dogara da Glutamine sun dogara ne akan jujjuyawar glutamine zuwa glutamate da glutamate metabolites don samar da makamashi da samar da tubalan ginin don samar da macromolecules, waɗanda ake buƙata don haɓakar salula da rayuwa.
Manufar: Glutaminase
