Saukewa: AMG-510
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 1g | a hannun jari | 1300 |
| 5g | a hannun jari | 6000 |
| 10 g | a hannun jari | 10500 |
Sunan Sinadari:
4- ((S) -4-acryloyl-2-methylpiperazin-1-yl) -6-fluoro-7- (2-fluoro-6-hydroxyphenyl) -1- (2-isopropyl-4-methylpyridin-3-yl) )pyrido[2,3-d]pyrimidin-2(1H) -daya
Lambar SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4=O)CC1
Lambar InChi:
InChi=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22 (24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
InChi Key:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Mabuɗin kalma:
AMG-510; AMG 510; Saukewa: AMG510
Solubility:
Ajiya:
Bayani:
AMG-510 shine mai hanawa mai ƙarfi na KRAS G12C. AMG-510 zaɓen yana hari da mutantan KRAS p.G12C, a ko dai DNA, RNA ko matakin furotin, kuma yana hana, ta hanyar da ba a fayyace ba tukuna, bayyanar da siginar ƙwayar ƙwayar cuta ta KRAS p.G12C. Wannan na iya hana girma a cikin KRAS p.G12C-bayyana ƙwayoyin ƙari
manufa: KRAS
