Ciforadenant

Sunan Sinadari:

(S) -7- (5-methylfuran-2-yl) -3-((6-(((tetrahydrofuran-3-yl) oxy)methyl) pyridin-2-yl) methyl) -3H-[1,2] ,3]triazolo[4,5-d]pyrimidin-5-amin

Lambar SMILES:

NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1

Lambar InChi:

InChi=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13- 3-2-4-14 (22-13) 10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/ t15-/m0/s1

InChi Key:

KURQKNMKCGYWRJ-HNNXBMFYSA-N

Mabuɗin kalma:

Ciforadenant, CPI-444, V81444, CPI444, CPI 444

Solubility:Mai narkewa a cikin DMSO

Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)

Bayani:

CPI-444 mai ƙarfi ne, samuwa a baki, mai zaɓaɓɓen antagonist na mai karɓar adenosine A2A wanda aka yarda da shi sosai a cikin binciken Ph 1 / 1b a cikin alamun rashin oncology.

Saukewa: Adenosine A2A