Vardenafil

Ainm Ceimigeach:

2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propyl-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a] [1,3,5] triazin-4-aon

Còd SMILES:

O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)(N]4(C)C3=CN(CCC)C4

Còd InChi:

InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20( 19) 33-7-3) 34(31,32)28-13-11-26(6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2,1- 4H3,(H,24,25,30)

iuchair InChi:

UWRWYSQUBZFWPU-UHFFAOYSA-N

Facal-luirg:

Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4

Solubility:Soluble ann an DMSO

Stòradh:0 - 4 ° C airson geàrr-ùine (làithean gu seachdainean), no -20 ° C airson ùine fhada (mìosan)

Tuairisgeul:

Tha Vardenafil, ris an canar cuideachd BAY 38-9456, na neach-dìon PDE5 air a chleachdadh airson làimhseachadh dysfunction erectile. Tha comharran agus frith-chomharran Vardenafil an aon rud ri luchd-dìon PDE5 eile; tha e dlùth cheangailte ann an gnìomh ri sildenafil citrate (Viagra) agus tadalafil (Cialis). Is e an eadar-dhealachadh eadar am moileciuil vardenafil agus sildenafil citrate suidheachadh nitrogen atom agus atharrachadh buidheann methyl ring piperazine sildenafil gu buidheann ethyl. Tha structar Tadalafil eadar-dhealaichte bho gach cuid sildenafil agus vardenafil. Tha ùine èifeachdach an ìre mhath goirid aig Vardenafil an coimeas ri ach beagan nas fhaide na ùine sildenafil.

Targaid: PDE5