Divarasib, GDC 6036
Mion-fhiosrachadh toraidh
Bathar Tags
| Meud pacaid | Ri fhaotainn | Prìs (USD) |
| 0.1G | Anns a’ bhùth | 550 |
| 0.5G | Anns a’ bhùth | 860 |
| 1G | Anns a’ bhùth | 1250 |
Ainm Ceimigeach:
1-(S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-il)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-il)methoxy)quinazolin-4-il)-3-methylpiperazin-1-il)prop-2-en-1-aon
Còd SMILES:
NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H)(CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F
Còd InChi:
InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33) 34) 15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)
iuchair InChi:
ZRBPIAWWRPFDPY-UHFFAOYSA-N
Facal-luirg:
2417987-45-0; CAS: 2417987-45-0; CAS: 2417987-45-0; sgaradh; GDC 6036
Solubility:Solubility Gus a dhearbhadh
Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).
Tuairisgeul:
Tha Divarasib (GDC-6036) na neach-dìon KRAS G12C le bith-ruigsinneachd beòil agus roghainn.
Targaid: KRAS G12C inhibitor
