Olutasidenib

Gemyske namme:

5-[[(1S)-1-(6-Chloor-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino]-1-methyl-6-oxo-1,6-dihydropyridine-2- karbonitril

SMILES Koade:

N#CC1=CC=C(N[C@H](C2=CC3=C(NC2=O)C=CC(Cl)=C3)C)C(N1C)=O

InChi Koade:

InChI=1S/C18H15ClN4O2/c1-10(21-16-6-4-13(9-20)23(2)18(16)25)14-8-11-7-12(19)3-5- 15(11)22-17(14)24/h3-8,10,21H,1-2H3,(H,22,24)/t10-/m0/s1

InChi Key:

NEQYWYXGTJDAKR-JTQLQIEISA-N

Keyword:

Olutasidenib; FT-2102; FT 2102; FT2102

Oplosberens:DMSO

Opslach: 

Beskriuwing:

Olutasidenib is in krêftige, selektive ynhibitor fan mutant Isocitrate dehydrogenase (IDH) 1 foar de behanneling fan akute myeloïde leukemy

Doel: IDH