Luxdegalutamide; ARV-766

Luxdegalutamide; ARV-766
  • Namme:4-(4-((1-(4-(((1r,3r)-3-(4-cyano-3-methoxyfenoksy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)fenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorbenzamide
  • Katalogusnûmer:CPD115335
  • CAS-nr.:2750830-09-0
  • Molekulêre gewicht:807.95
  • Gemyske formule:C45 H54 F N7 O6
  • Allinich foar wittenskiplik ûndersyk, net foar pasjinten.

    Produkt Detail

    Produkt Tags

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    Gemyske namme:

    4-(4-((1-(4-(((1r,3r)-3-(4-cyano-3-methoxyfenoksy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)fenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorbenzamide

    SMILES Koade:

    CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F)=C(C(N[C@@H]6C(=O)NC(=O) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1

    InChi Koade:

    InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)58-5)50- 39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23-21-51)32- 11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28,36, 42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0/s1

    InChi Key:

    RDPPBRKNBBXPNZ-FMPIRMQTSA-N

    Keyword:

    2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0;ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide

    Oplosberens: 

    Opslach:Droog, tsjuster en by 0 - 4 C foar koarte termyn (dagen oant wiken) of -20 C foar lange termyn (moannen oant jierren).

    Beskriuwing:

    Luxdegalutamide (ARV-766) is in oraal effektive proteïnehydrolyse-targete chimeric (PROTAC) targeting androgen receptor (AR), dy't AR-resistinsje relatearre mutanten kin degradearje.

    Doel: AR




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