lirafugratinib; RLY-4008

Gemyske namme:

N-[4-(4-amino-5-{3-fluor-4-[(4-methylpyrimidin-2-yl)oxy]fenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- 6-yl)phenyl]-2-methylprop-2-enamide

SMILES Koade:

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N= CN=C5N2C)C=C1)=O

InChi Koade:

InChI=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26( 23)36(24 )4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2-4H3,(H, 35,37)(H2,30,32,33)

InChi Key:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

Keyword:

2549174-42-5；CAS：2549174-42-5；CAS:2549174-42-5；Lirafugratinib; RLY-4008; RLY 4008; RLY4008

Oplosberens: 

Opslach:Droog, tsjuster en by 0 - 4 C foar koarte termyn (dagen oant wiken) of -20 C foar lange termyn (moannen oant jierren).

Beskriuwing:

Lirafugratinib (RLY-4008) is in oraal aktive, irreversibele en tige selektive FGFR2-ynhibitor.

Doel: FGFR2