BI-3812

Gemyske namme:

1-(5-Chloor-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidine -2-yl)-N,N-dimethylpiperidine-4-carboxamide

SMILES Koade:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

InChi Koade:

InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18( 27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1- 5H3,(H,28,35)(H,29,30,31)

InChi Key:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Keyword:

BI-3812; BI 3812; BI3812

Oplosberens: 

Opslach: 

Beskriuwing:

BI-3812 is in krêftige ynhibitor fan 'e ynteraksje fan it BTB / POZ-domein fan BCL6 mei ferskate ko-repressors. It wurket troch inhibiting fan de BCL6 :: Co-repressor kompleks formaasje.

Doel: BCL6