BAY-299
Produkt Detail
Produkt Tags
| Pak Grutte | Beskikberens | Priis (USD) |
| 100mg | In stock | 500 |
| 500mg | In stock | 800 |
| 1g | In stock | 1200 |
| Mear maten | Get Quotes | Get Quotes |
Gemyske namme:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3( 2H)-dion
SMILES Koade:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
InChi Koade:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8- 4-7-16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6, 11H2,1-3H3
InChi Key:
OFWWWKWUCDUISA-UHFFFAOYSA-N
Keyword:
BAY-299, BAY 299, BAY 299, 2080306-23-4
Oplosberens:Oplosber yn DMSO
Opslach:0 - 4 ° C foar koarte termyn (dagen oant wiken), of -20 ° C foar lange termyn (moannen).
Beskriuwing:
BAY-299 is in krêftige en selektive ynhibitor fan it bromodomain en PHD finger-befette (BRPF) famyljeprotein BRD1 (IC50 = 6 nM), ek wol bekend as BRPF2, en it twadde bromodomein fan transkripsje-inisjatyffaktor TFIID subunits 1 (TAF1; IC50) = 13 nM).1 BAY-299 is >30 kear selektyf oer BRPF1, BRPF3, BRD9, en ATAD2 en is>300-fâld selektyf oer BRD4.
Doel: BRPF