Ziftomenib ；KO539

Enw:(S)-4-Methyl-5-((4-((2-(methylamino))-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitril

Rhif catalog:DPP113642

Rhif CAS:2134675-36-6

Pwysau moleciwlaidd:717.87

Fformiwla Cemegol:C33 H42 F3 N9 O2 S2

Ar gyfer ymchwil wyddonol yn unig, nid ar gyfer cleifion.

Anfonwch e-bost atom Lawrlwythwch fel PDF

Manylion Cynnyrch

Tagiau Cynnyrch

Maint Pecyn	Argaeledd	Pris (USD)
0.1G	Mewn Stoc	650
0.5G	Mewn Stoc	970
1G	Mewn Stoc	1350

Enw Cemegol:

(S)-4-Methyl-5-((4-((2-(methylamino))-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitril

Cod gwenu:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F))) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Cod InChi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2) 23(5-6-29(27)45)20-42-9-7-24(8-10-42)39-30-28-16-26(17-33(34,35)36)48- 31(28)41-32(38-3)40-30/h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40 ,41)/t21-/m0/s1

Allwedd InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Allweddair:

2134675-36-6 ； CAS: 2134675-36-6 ； CAS: 2134675-36-6 ；Ziftomenib; KO539; KO 539; KO-539

Hydoddedd:I'w benderfynu

Storio:Sych, tywyll ac ar 0 - 4 C am dymor byr (dyddiau i wythnosau) neu -20 C am dymor hir (misoedd i flynyddoedd).

Disgrifiad:

Mae Ziftomenib (KO-539) yn atalydd rhyngweithiad menin MLL â gweithgaredd llafar.

Targed: menin-MLL

Pâr o: 4,6-dichloro-5-fflworo-2-Methanesulfonyl-pyriMidine

Nesaf: N-Methyl-5-(piperazin-1-yl) hydroclorid picolinamide