Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Enw Cemegol:

(2R)-N-(3-{5-fflworo-2-[2-fflworo-3-(methanesulfonyl)anilino]pyrimidin-4-yl}-1H-indol-7-yl)-3-methoxy-2- (4-methylpiperazin-1-yl)propanamide

Cod gwenu:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)(C@H)(N5CCN(C)) )CC5)COC

Cod InChi:

InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/ h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

Allwedd InChi:

JNUZADQZHYFJGW-JOCHJYFZSA-N

Allweddair:

2241039-81-4 ； CAS: 2241039-81-4 ； CAS: 2241039-81-4 ；Londamocitinib；JAK1-IN-7；AZD4604；AZD-4604；JAC34RRR7S

Hydoddedd: 

Storio:Sych, tywyll ac ar 0 - 4 C am dymor byr (dyddiau i wythnosau) neu -20 C am dymor hir (misoedd i flynyddoedd).

Disgrifiad:

Mae Londamocitinib (AZD4604) yn atalydd JAK1 detholus effeithiol.

Targed: JAK1