Ifebemtinib, BI 853520

Enw Cemegol:

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fflworo- 5-methoxy-N-(1-methyl-4-piperidinyl)benzamid

Cod gwenu:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O))= N3)C=C2F

Cod InChi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,31)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/ h4-6,11-13,16H,7-10,14H2,1-3H3,(H,34,39)(H,33,35,36)

Allwedd InChi:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Allweddair:

1227948-82-4 ； CAS: 1227948-82-4 ； CAS: 1227948-82-4 ；Ifebemtinib；BI 853520

Hydoddedd:Hydawdd mewn DMSO, nid mewn dŵr

Storio:0 - 4 C am dymor byr (dyddiau i wythnosau), neu -20 C am dymor hir (misoedd).

Disgrifiad:

Mae Ifebemtinib (BI 853520) yn atalydd cryf o kinase adlyniad ffocal (FAK) gyda gweithgaredd llafar.

Targed: Atalydd Cryf FAK