Dapagliflozin Propanediol Monohydrate

Enw Cemegol:

5-[5-Phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridine-3-sulfonamide

Cod gwenu:

O=S(C1=CC(C2=NC(NCC3=NC=CC=C3)=C4C(C5=CC=CC=C5)=CC=CC4=N2)=CN=C1)(N)=O

Cod InChi:

InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1- 3 -8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33) (H,29,30,31)

Allwedd InChi:

XGKULQQVQWCASY-UHFFFAOYSA-N

Allweddair:

960404-48-2 ； CAS:960404-48-2 ； CAS: 960404-48-2 ；Dapagliflozin Propanediol Monohydrate

Hydoddedd:Hydawdd mewn DMSO

Storio:0 - 4 C am dymor byr (dyddiau i wythnosau), neu -20 C am dymor hir (misoedd).

Disgrifiad:

Dapagliflozin ((2S) -1,2-propanediol, hydrad) yw'r isomer S o Dapagliflozin 1,2-propanediol, hydrad, a ddefnyddir wrth astudio diabetes (DM), yn atalydd cystadleuol o cotransporter glwcos 2 (SGLT2), a all arwain at ysgarthiad glwcos mewn wrin.

Targed: atalydd SGLT2