BI-3812

Enw Cemegol:

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin -2-yl)-N,N-dimethylpiperidine-4-carboxamide

Cod gwenu:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C)C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Cod InChi:

InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18( 27) 13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1- 5H3,(H,28,35)(H,29,30,31)

Allwedd InChi:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Allweddair:

BI-3812; BI 3812; BI3812

Hydoddedd: 

Storio: 

Disgrifiad:

Mae BI-3812 yn atalydd cryf o ryngweithiad parth BTB/POZ o BCL6 gyda sawl cyd-wrthwasgydd. Mae'n gweithredu trwy atal ffurfiant cymhleth BCL6 :: Cyd-repressor.

Targed: BCL6