| CAT # | Naziv proizvoda | Opis |
| CPD3611 | SB-204990 | SB-204990 je prolijek snažnog inhibitora ATP citrat-liaze SB-201076. SB-204990, kada se oralno davao pacovima, apsorbirao se u sistemsku cirkulaciju, farmakološki relevantne koncentracije SB-201076 su pronađene u jetri. SB-204990 (25 mg/kg dnevno) je također smanjio nivo holesterola u plazmi (do 23%) i nivoe triglicerida (do 38%) kod psa, prvenstveno smanjujući lipoproteine niske gustine u poređenju sa holesterolom lipoproteina visoke gustine nivoa. SB-204990 je važan enzim u kontroli opskrbe supstratom za sintezu lipida de novo i potencijalna meta enzima za hipolipidemijsku intervenciju. |
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