STING agonist-4

የኬሚካል ስም

1,1'- (ቡቴን-1,4-ዲይል) ቢስ (2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo [d] imidazole-5-carboxamide)

የፈገግታ ኮድ፡-

O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC) (ሐ)=NN6CC)=ኦ)=NC2=C1)N

የኢንቺ ኮድ

InChi=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11- 25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50) 28-16-20(4)42-46(28)6-2/h9-12፣15-18H፣5-8፣13-14H2፣1-4H3፣(H2፣35፣47)(H2,36፣ 48)(H,37,39,49)(H,38,40,50)

የኢንቺ ቁልፍ፡

ICZSAXDKFXTSGL-UHFFFAOYSA-N

ቁልፍ ቃል፡

መሟሟት; 

ማከማቻ፡ 

መግለጫ፡-

STING agonist-4 የ Interferon Genes (STING) ተቀባይ ተቀባይ አበረታች ነው (IC50) የ 20 nM. STING agonist-4 ከSTING እና ከሴሉላር ተግባር ጋር የተሻሻለ ትስስር ያለው ABZI (diABZI) ለመፍጠር ከሲሜትሜትሪ ጋር የተገናኘ amidobenzimidazole (ABZI) የተመሰረተ ውህድ ነው።

ዓላማ፡ STING