| ድመት # | የምርት ስም | መግለጫ |
| ሲፒዲቢ1974 | GSK-461364 | GSK461364 ዶዝ-ጥገኛ በተለያዩ የካንሰር ሴል መስመሮች ውስጥ የሕዋስ ብስክሌትን ያስቆማል እና ከፍ ባለ መጠን አፖፕቶሲስን ያነሳሳል። በ p53 ጉድለት እጢዎች ላይ የበለጠ ውጤታማ ሆኖ ይታያል እና የደም-አንጎል እንቅፋትን ማለፍ ይችላል። GSK461364 በአይጦች ውስጥ የ xenograft ሞዴሎችን የዕጢ እድገት መከልከልን ወይም የእድገት መዘግየትን በመፍጠር በ Vivo ውስጥ ውጤታማ ነው። |
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