diABZI STING agonist-1 trihydrochloride

የኬሚካል ስም

(ኢ) -1- (4- (5-carbamoyl-2-- 1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7- (3-morpholinopropoxy)-1H-benzo [d] imidazole -1-yl) ግን-2-en-1-yl)-2-(1-ኤቲል-3-ሜቲኤል-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5- ካርቦክስሚድ trihydrochloride

የፈገግታ ኮድ፡-

O=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=ኦ) =NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O=C6)=C3C(OC)=C1.Cl.Cl.Cl

የኢንቺ ኮድ

CKESNWHACHILIV-BILRHTGOSA-N

የኢንቺ ቁልፍ፡

InChi=1S/C42H51N13O7.3ClH/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(4) 3)56)23-33(60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20- 26(4)50- 55(32)7-2)22-28(38(44)57)24-34(36)62-16-10-11-51-14-17-61-18-15-51;;/h8 -9፣19-2 4H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59);3*1H /b9-8+;;;

ቁልፍ ቃል፡

መሟሟት; 

ማከማቻ፡ 

መግለጫ፡-

diABZI STING agonist-1 (trihydrochloride) የኢንተርፌሮን ጂኖች (STING) ተቀባይ ተቀባይ አበረታች ነው፣ EC50s ያለው 130፣ 186 nM ለሰው እና ለአይጥ በቅደም ተከተል።

ዓላማ፡ STING