Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Chemiese naam:

(2R)-N-(3-{5-fluoro-2-[2-fluoro-3-(metaansulfoniel)anilino]pirimidien-4-iel}-1H-indool-7-yl)-3-metoksi-2- (4-metielpiperasien-1-yl)propaanamied

SMILES-kode:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)[C@H](N5CCN(C) )CC5)COC

InChi-kode:

InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21)25-19(29)15-32 -28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/h4-9,14-15,22,31H,10-13,16H2 ,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

InChi-sleutel:

JNUZADQZHYFJGW-JOCHJYFZSA-N

Sleutelwoord:

2241039-81-4；CAS：2241039-81-4；CAS:2241039-81-4；Londamocitinib；JAK1-IN-7；AZD4604；AZD-4604；JAC34RRR7

Oplosbaarheid: 

Berging:Droog, donker en by 0 - 4 C vir kort termyn (dae tot weke) of -20 C vir lang termyn (maande tot jare).

Beskrywing:

Londamocitinib (AZD4604) is 'n effektiewe selektiewe JAK1-remmer.

Teiken: JAK1