GDC6036; GDC6036 atropisomere

Chemiese naam:

2-Propen-1-on, 1-[(3S)-4-[7-[6-amino-4-metiel-3-(trifluorometiel)-2-piridiniel]-6-chloor-8-fluoro-2- [[(2S)-1-metiel-2-pirrolidiniel]metoksi]-4-kinasoliniel]-3-metiel-1-piperasieniel]-

SMILES Kode:

C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F) )C3=NC(OC[C@H]5N(C)CCC5)=N2)CC1)=O

InChi-kode:

InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33)34)15(2)11-20(35)36-2 6)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6- 10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

InChi-sleutel:

ZRBPIAWWRPFDPY-IRXDYDNUSA-N

Sleutelwoord:

2417917-17-8；CAS：2417917-17-8；CAS:2417917-17-8；GDC6036 atropisomere; GDC-6036; GDC 6036; GDC6036

Oplosbaarheid: 

Berging:Droog, donker en by 0 - 4 C vir kort termyn (dae tot weke) of -20 C vir lang termyn (maande tot jare).

Beskrywing:

Die GDC6036 anti-rotasie-isomeer bevat twee tipes GDC6036 anti-rotasie-isomere. GDC-6036， Ook bekend as RG6330, dit is 'n oraal biobeskikbare, hoogs doeltreffende en selektiewe KRAS G12C-remmer.

Teiken: KRAS G12C