I-VPS34-IN1

Igama:1-((2-((2-chloropyridin-4-yl)amino)-4'-(cyclopropylmethyl)-[4,5'-bipyrimidin]-2'-yl)amino)-2-methylpropan-2-ol

Inombolo yekhathalogi:I-CPD108302

Inombolo ye-CAS:1383716-33-3

Isisindo se-Molecular:425.91

I-Chemical Formula:I-C21 H24 Cl N7 O

Olocwaningo lwesayensi kuphela, hhayi lweziguli.

Thumela i-imeyili kithi Landa njenge-PDF

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Usayizi Wephakethe	Ukutholakala	Intengo (USD)
0.1G	Kukhona kusitoki	520
0.5G	Kukhona kusitoki	1120
1G	Kukhona kusitoki	1650

Igama Lekhemikhali:

1-((2-((2-chloropyridin-4-yl)amino)-4'-(cyclopropylmethyl)-[4,5'-bipyrimidin]-2'-yl)amino)-2-methylpropan-2-ol

Ikhodi ye-SMILES:

OC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3

Ikhodi ye-InChi:

I-InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24- 20(28-1 6)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26 ,29)(H,23,24,27,28)

I-InChi Key:

AWNXKZVIZARMME-UHFFFAOYSA-N

Igama elingukhiye:

1383716-33-3;CAS:1383716-33-3;CAS:1383716-33-3;VPS34IN1, VPS34 IN1, VPS34-IN1

Ukunyibilika:Incibilika ku-DMSO, hhayi emanzini

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Vps34-IN-1 iyisivimbeli sesigaba III Vps34 PI3K esisebenzayo nesikhethiwe.

Ithagethi: Vps34 PI3K

Okwedlule: I-VT-105

Olandelayo: I-PRT 543; C220; I-PRMT5 inhibitor