I-PRT 543; C220; I-PRMT5 inhibitor

Igama Lekhemikhali:

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chlorophenyl)-hydroxymethyl]oxolane-3,4 -diol

Ikhodi ye-SMILES:

O[C@H]1[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H]([C@@H](C4=CC=C(Cl)C =C4)O)[C@H]1O

Ikhodi ye-InChi:

I-InChI=1S/C17H17ClN4O4/c18-9-3-1-8(2-4-9)11(23)14-12(24)13(25)17(26-14)22-6-5-10- 15(19)20-7-21-16(10)22/h1-7,11-14,17,23-25H,(H2,19,20,21)/t11-,12+,13-,14 -,17-/m1/s1

I-InChi Key:

ITEKIFMGFZAFPM-QFRSUPTLSA-N

Igama elingukhiye:

1989620-03-2;CAS:1989620-03-2;CAS:1989620-03-2;PRT-543; I-PRT543; I-PRT 543; C220; I-PRMT5 inhibitor; I-PRMT5 inhibitor C220

Ukunyibilika: 

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-PRMT5-IN-35 (Inhlanganisela 87) iyisivimbi esisebenzayo esikhethiwe futhi esisebenza ngomlomo se-PRMT5.

Ithagethi: PRMT5