I-Trelagliptin

I-Trelagliptin
  • Igama:I-Trelagliptin
  • Inombolo yekhathalogi:I-CPDA0088
  • Inombolo ye-CAS:865759-25-7(isisekelo samahhala); 1029877-94-8(Succinate)
  • Isisindo se-Molecular:357.38
  • I-Chemical Formula:I-C18H20FN5O2
  • Olocwaningo lwesayensi kuphela, hhayi lweziguli.

    Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Usayizi Wephakethe Ukutholakala Intengo (USD)

    Igama Lekhemikhali:

    (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

    Ikhodi ye-SMILES:

    N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

    Ikhodi ye-InChi:

    I-InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14( 19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1

    I-InChi Key:

    IWYJYHUNXVAVAA-OAHLLOKOSA-N

    Igama elingukhiye:

    Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

    Ukunyibilika:I-Soluble ku-DMSO

    Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

    Incazelo:

    I-Trelagliptin, eyaziwa nangokuthi i-SYR-472, iyi-inhibitor ye-dipeptidyl peptidase-4 (DPP-4) esebenza isikhathi eside eyakhiwa i-Takeda ukuze ikwelapha uhlobo 2 sikashukela (T2D). Ukwelashwa kwe-SYR-472 kanye ngesonto kukhiqize ukuthuthuka okubalulekile ngokomtholampilo nangezibalo ekulawuleni i-glycemic ezigulini ezinesifo sikashukela sohlobo 2. Kubekezelelwe kahle futhi kungase kube indlela entsha yokwelapha ezigulini ezinalesi sifo. I-Trelagliptin (i-Zafatek(®)) yagunyazwa e-Japan yokwelapha uhlobo 2 lwesifo sikashukela i-mellitus (T2DM).

    Ithagethi: DPP-4


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