I-STING agonist-4

I-STING agonist-4
  • Igama:I-STING agonist-4
  • Inombolo yekhathalogi:I-CPD101232
  • Inombolo ye-CAS:2138300-40-8
  • Isisindo se-Molecular:678.74
  • I-Chemical Formula:C34 H38 N12 O4
  • Olocwaningo lwesayensi kuphela, hhayi lweziguli.

    Imininingwane Yomkhiqizo

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    Usayizi Wephakethe Ukutholakala Intengo (USD)

    Igama Lekhemikhali:

    1,1'-(butane-1,4-diyl) bis(2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazole-5-carboxamide)

    Ikhodi ye-SMILES:

    O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC) (C)=NN6CC)=O)=NC2=C1)N

    Ikhodi ye-InChi:

    I-InChI=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11- 25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50) 28-16-20(4)42-46(28)6-2/h9-12,15-18H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36, 48)(H,37,39,49)(H,38,40,50)

    I-InChi Key:

    I-ICZSAXDKFXTSGL-UHFFFAOYSA-N

    Igama elingukhiye:

    Ukunyibilika: 

    Isitoreji: 

    Incazelo:

    I-STING agonist-4 iyisikhuthazi se-Interferon Genes (STING) receptor agonist ene-apparent inhibitory constant (IC50) yama-20 nM. I-STING agonist-4 iyinhlanganisela esekelwe ku-symmetry ehlobene ne-amidobenzimidazole (ABZI) ukuze idale ama-ABZI axhunyiwe (diABZIs) abophezelekile ku-STING kanye nomsebenzi weselula.

    Ithagethi: STING


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