I-STING

IKATI # Igama Lomkhiqizo Incazelo
I-CPD101235 I-diABZI STING agonist-1 trihydrochloride I-diABZI STING agonist-1 (trihydrochloride) iyisikhuthazi esikhethiwe sezakhi zofuzo ze-interferon (STING) receptor agonist, nama-EC50s angu-130, 186 nM womuntu negundane, ngokulandelana.
I-CPD101234 I-diABZI STING agonist-1 (Tautomerism) I-diABZI STING agonist-1 Tautomerism (inhlanganisela 3) iyisikhuthazi esikhethiwe sezakhi zofuzo ze-interferon (STING) receptor agonist, nama-EC50s angu-130, 186 nM womuntu negundane, ngokulandelana.
I-CPD101233 i-diABZI STING agonist-1 I-diABZI STING agonist-1 iyisikhuthazi esikhethiwe sezakhi zofuzo ze-interferon (STING) receptor agonist, nama-EC50s angu-130, 186 nM womuntu negundane, ngokulandelana.
I-CPD101232 I-STING agonist-4 I-STING agonist-4 iyisikhuthazi se-Interferon Genes (STING) receptor agonist ene-apparent inhibitory constant (IC50) yama-20 nM. I-STING agonist-4 iyinhlanganisela esekelwe ku-symmetry ehlobene ne-amidobenzimidazole (ABZI) ukuze idale ama-ABZI axhunyiwe (diABZIs) abophezelekile ku-STING kanye nomsebenzi weselula.
I-CPD101231 I-STING agonist-3 I-STING agonist-3, ekhishwe ku-patent WO2017175147A1 (isibonelo 10), iyi-agonist ekhethiwe futhi engeyona i-nucleotide ye-molecule encane ye-STING ene-pEC50 ne-pIC50 ye-7.5 kanye ne-9.5, ngokulandelanayo. I-STING agonist-3 inomphumela oqinile wokulwa nesimila namandla amakhulu okuthuthukisa ukwelashwa komdlavuza
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