Momelotinib;CTY387

Orukọ Kemikali:

N- (cyanomethyl) -4- (2- ((4-morpholinophenyl) amino) pyrimidin-4-yl) benzamide

KỌỌDỌ SMILES:

O=C(NCC#N)C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1

Koodu InChi:

InChi=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)2 7-19-5-7-20 (8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H, 26,27,28)

Bọtini InChi:

ZVHNDZWQTBEVRY-UHFFFAOYSA-N

Koko-ọrọ:

1056634-68-4

Solubility:Tiotuka ni DMSO, DMF

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Momelotinib (CYT387) jẹ oludena JAK1/JAK2 ifigagbaga ti ATP.

Àfojúsùn: JAK1/JAK2