Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Orukọ Kemikali:

(2R)-N-(3-{5-fluoro-2-[2-fluoro-3-(methanesulfonyl)anilino]pyrimidin-4-yl}-1H-indol-7-yl)-3-methoxy-2- (4-methylpiperazin-1-yl) propanamide

KỌỌDỌ SMILES:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)[C@H](N5CCN(C) )CC5)COC

Koodu InChi:

InChi=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/ h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

Bọtini InChi:

JNUZADQZHYFJGW-JOCHJYFZSA-N

Koko-ọrọ:

2241039-81-4;CAS:2241039-81-4;CAS:2241039-81-4;Londamocitinib;JAK1-IN-7：AZD4604；AZD-4604；JAC34RRR

Solubility: 

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Londamocitinib (AZD4604) jẹ oludena JAK1 yiyan ti o munadoko.

afojusun: JAK1