MDK7526 HCl

MDK7526 HCl
  • Orukọ:MDK7526 HCl; Protein degrader 1 hydrochloride
  • Katalogi No.CPDB1584
  • CAS No.:1448189-80-7
  • Ìwọ̀n Molikula:467.025
  • Fọọmu Kemikali:C22H31ClN4O3S
  • Fun iwadi ijinle sayensi nikan, kii ṣe fun awọn alaisan.

    Alaye ọja

    ọja Tags

    Iwọn Pack Wiwa Iye owo (USD)
    100mg O wa 500
    500mg O wa 800
    1g O wa 1200
    Awọn iwọn diẹ sii Gba Awọn asọye Gba Awọn asọye

    Orukọ Kemikali:

    (2S,4R) -1- ((S) -2-amino-3,3-dimethylbutanoyl) -4-hydroxy-N- (4- (4-methylthiazol-5-yl) benzyl) pyrrolidine-2-carboxamide hydrochloride

    KỌỌDỌ SMILES:

    O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

    Koodu InChi:

    InChi=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27) 11-26 (1 7)21 (29)19 (23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28) ;1H/t16-,17+,19-;/m1./s1

    Bọtini InChi:

    JYRTWGCWUBURGU-MSSRUXLCSA-N

    Koko-ọrọ:

    MDK7526 HCl, Protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

    Solubility:Tiotuka ni DMSO

    Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu).

    Apejuwe:

    MDK7526, tun mo bi VHL Ligand 1; Protein degrader 1, jẹ apanirun amuaradagba ti o lagbara ati yiyan. MDK7526 ni CAS # 1448297-52-6, iyọ HCl rẹ ni CAS # 1448189-80-7. MDK7526 jẹ agbara ti o wulo fun ibajẹ ìfọkànsí ti olugba androgen. MDK7526 sopọ awọn olugba androgen gẹgẹbi pe a gbe olugba androgen ni isunmọ si ligase ubiquitin lati ṣe ipa degrdn. (ati idinamọ) ti androgen receptor.

    Afojusun: Androgen Olugba


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