LOXO-305; LY 3527727; Pirtobrutinib

Orukọ Kemikali:

(S) -5-amino-3- (4- ((5-fluoro-2-methoxybenzamido)methyl) phenyl) -1- (1,1,1-trifluoropropan-2-yl) -1H-pyrazole-4- carboxamide

KỌỌDỌ SMILES:

O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N

Koodu InChi:

InChi = 1S/C22H21F4N5O3/c1-11 13)10 -29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H) ,29,33)/t11-/m0/s1

Bọtini InChi:

FWZAWAUZXYCBKZ-NSHDSACASA-N

Koko-ọrọ:

2101700-15-4;CAS:2101700-15-4;CAS:2101700-15-4;LOXO-305;LOXO 305;LOXO305;LY 3527727;LY-3527727;LY3527727;Pirtobrutinib

Solubility: 

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Pirtobrutinib (LOXO-305) jẹ yiyan ti o ga pupọ ati inhibitor BTK iran-tẹle ti o le ṣe idiwọ ọpọlọpọ awọn iyipada iyipada BTK C481.

afojusun: BTK