Lirafugratinib; RLY-4008

Orukọ Kemikali:

N-[4- (4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- 6-yl) phenyl] -2-methylprop-2-enamide

KỌỌDỌ SMILES:

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N= CN=C5N2C)C=C1)=O

Koodu InChi:

InChi=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26( 23)36(24). )4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2-4H3,(H, 35,37) (H2,30,32,33)

Bọtini InChi:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

Koko-ọrọ:

2549174-42-5;CAS:2549174-42-5;CAS:2549174-42-5;Lirafugratinib; RLY-4008; RLY 4008; RLY4008

Solubility: 

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Lirafugratinib (RLY-4008) jẹ ohun ti nṣiṣe lọwọ ẹnu, ti ko le yi pada, ati oludanujẹ FGFR2 yiyan pupọ.

Ifojusi: FGFR2